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A Novel Domain Cassette Identifies Plasmodium falciparum PfEMP1 Proteins Binding ICAM-1 and Is a Target of Cross-Reactive, Adhesion-Inhibitory Antibodies

Cerebral Plasmodium falciparum malaria is characterized by adhesion of infected erythrocytes (IEs) to the cerebral microvasculature. This has been linked to parasites expressing the structurally related group A subset of the P. falciparum erythrocyte membrane protein 1 (PfEMP1) family of IE adhesion...

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Detalhes bibliográficos
Main Authors: Bengtsson, Anja, Joergensen, Louise, Rask, Thomas S., Olsen, Rebecca W., Andersen, Marianne A., Turner, Louise, Theander, Thor G., Hviid, Lars, Higgins, Matthew K., Craig, Alister, Brown, Alan, Jensen, Anja T. R.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3539686/
https://ncbi.nlm.nih.gov/pubmed/23209327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202578
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