Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiation

Fibroblast to myofibroblast differentiation is crucial for the initial healing response but excessive myofibroblast activation leads to pathological fibrosis. Therefore, it is imperative to understand the mechanisms underlying myofibroblast formation. Here we report that mitochondrial calcium ((m)Ca...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Lombardi, Alyssa A., Gibb, Andrew A., Arif, Ehtesham, Kolmetzky, Devin W., Tomar, Dhanendra, Luongo, Timothy S., Jadiya, Pooja, Murray, Emma K., Lorkiewicz, Pawel K., Hajnóczky, György, Murphy, Elizabeth, Arany, Zoltan P., Kelly, Daniel P., Margulies, Kenneth B., Hill, Bradford G., Elrod, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778142/
https://ncbi.nlm.nih.gov/pubmed/31586055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12103-x
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