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Efficient inter-species conjugative transfer of a CRISPR nuclease for targeted bacterial killing

The selective regulation of bacteria in complex microbial populations is key to controlling pathogenic bacteria. CRISPR nucleases can be programmed to kill bacteria, but require an efficient and broad-host range delivery system to be effective. Here, using an Escherichia coli and Salmonella enterica...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Hamilton, Thomas A., Pellegrino, Gregory M., Therrien, Jasmine A., Ham, Dalton T., Bartlett, Peter C., Karas, Bogumil J., Gloor, Gregory B., Edgell, David R.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778077/
https://ncbi.nlm.nih.gov/pubmed/31586051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12448-3
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