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Efficient inter-species conjugative transfer of a CRISPR nuclease for targeted bacterial killing

The selective regulation of bacteria in complex microbial populations is key to controlling pathogenic bacteria. CRISPR nucleases can be programmed to kill bacteria, but require an efficient and broad-host range delivery system to be effective. Here, using an Escherichia coli and Salmonella enterica...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nat Commun
Päätekijät: Hamilton, Thomas A., Pellegrino, Gregory M., Therrien, Jasmine A., Ham, Dalton T., Bartlett, Peter C., Karas, Bogumil J., Gloor, Gregory B., Edgell, David R.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778077/
https://ncbi.nlm.nih.gov/pubmed/31586051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12448-3
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