Efficient inter-species conjugative transfer of a CRISPR nuclease for targeted bacterial killing

The selective regulation of bacteria in complex microbial populations is key to controlling pathogenic bacteria. CRISPR nucleases can be programmed to kill bacteria, but require an efficient and broad-host range delivery system to be effective. Here, using an Escherichia coli and Salmonella enterica...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Hamilton, Thomas A., Pellegrino, Gregory M., Therrien, Jasmine A., Ham, Dalton T., Bartlett, Peter C., Karas, Bogumil J., Gloor, Gregory B., Edgell, David R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778077/
https://ncbi.nlm.nih.gov/pubmed/31586051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12448-3
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