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Chronic inflammation directs an olfactory stem cell functional switch from neuroregeneration to immune defense

Although olfactory mucosa possesses long-lived horizontal basal stem cells (HBCs) and remarkable regenerative capacity, the function of human olfactory neuroepithelium is significantly impaired in chronic inflammatory rhinosinusitis. Here we show that while inflammation initially damages olfactory n...

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Enregistré dans:
Détails bibliographiques
Publié dans:Cell Stem Cell
Auteurs principaux: Chen, Mengfei, Reed, Randall R., Lane, Andrew P.
Format: Artigo
Langue:Inglês
Publié: 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778045/
https://ncbi.nlm.nih.gov/pubmed/31523027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2019.08.011
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