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Chronic inflammation directs an olfactory stem cell functional switch from neuroregeneration to immune defense

Although olfactory mucosa possesses long-lived horizontal basal stem cells (HBCs) and remarkable regenerative capacity, the function of human olfactory neuroepithelium is significantly impaired in chronic inflammatory rhinosinusitis. Here we show that while inflammation initially damages olfactory n...

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Publicat a:Cell Stem Cell
Autors principals: Chen, Mengfei, Reed, Randall R., Lane, Andrew P.
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778045/
https://ncbi.nlm.nih.gov/pubmed/31523027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2019.08.011
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