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Chronic inflammation directs an olfactory stem cell functional switch from neuroregeneration to immune defense

Although olfactory mucosa possesses long-lived horizontal basal stem cells (HBCs) and remarkable regenerative capacity, the function of human olfactory neuroepithelium is significantly impaired in chronic inflammatory rhinosinusitis. Here we show that while inflammation initially damages olfactory n...

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Bibliografiska uppgifter
I publikationen:Cell Stem Cell
Huvudupphovsmän: Chen, Mengfei, Reed, Randall R., Lane, Andrew P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778045/
https://ncbi.nlm.nih.gov/pubmed/31523027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2019.08.011
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