N6-methyladenosine modification controls circular RNA immunity

Circular RNAs (circRNAs) are prevalent in eukaryotic cells and viral genomes. Mammalian cells possess innate immunity to detect foreign circRNAs, but the molecular basis of self vs. foreign identity in circRNA immunity is unknown. Here we show that N6-methyladenosine (m(6)A) RNA modification on huma...

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Detaylı Bibliyografya
Yayımlandı:Mol Cell
Asıl Yazarlar: Chen, Y. Grace, Chen, Robert, Ahmad, Sadeem, Verma, Rohit, Kasturi, Sudhir, Amaya, Laura, Broughton, James P., Kim, Jeewon, Cadena, Cristhian, Pulendran, Bali, Hur, Sun, Chang, Howard Y.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778039/
https://ncbi.nlm.nih.gov/pubmed/31474572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.07.016
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