N6-methyladenosine modification controls circular RNA immunity

Circular RNAs (circRNAs) are prevalent in eukaryotic cells and viral genomes. Mammalian cells possess innate immunity to detect foreign circRNAs, but the molecular basis of self vs. foreign identity in circRNA immunity is unknown. Here we show that N6-methyladenosine (m(6)A) RNA modification on huma...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Chen, Y. Grace, Chen, Robert, Ahmad, Sadeem, Verma, Rohit, Kasturi, Sudhir, Amaya, Laura, Broughton, James P., Kim, Jeewon, Cadena, Cristhian, Pulendran, Bali, Hur, Sun, Chang, Howard Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6778039/
https://ncbi.nlm.nih.gov/pubmed/31474572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2019.07.016
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