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A biodegradable nanocapsule delivers a Cas9 ribonucleoprotein complex for in vivo genome editing
Delivery technologies for the CRISPR-Cas9 gene editing system often require viral vectors, which pose safety concerns for therapeutic genome editing(1). Alternatively, cationic liposomal components or polymers can be used to encapsulate multiple CRISPR components into large particles (typically >...
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| Publicado no: | Nat Nanotechnol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6778035/ https://ncbi.nlm.nih.gov/pubmed/31501532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41565-019-0539-2 |
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