Myogenic vasoconstriction requires G(12)/G(13) and LARG to maintain local and systemic vascular resistance

Myogenic vasoconstriction is an autoregulatory function of small arteries. Recently, G-protein-coupled receptors have been involved in myogenic vasoconstriction, but the downstream signalling mechanisms and the in-vivo-function of this myogenic autoregulation are poorly understood. Here, we show tha...

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Vydáno v:eLife
Hlavní autoři: Chennupati, Ramesh, Wirth, Angela, Favre, Julie, Li, Rui, Bonnavion, Rémy, Jin, Young-June, Wietelmann, Astrid, Schweda, Frank, Wettschureck, Nina, Henrion, Daniel, Offermanns, Stefan
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2019
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777979/
https://ncbi.nlm.nih.gov/pubmed/31549965
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49374
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