G(q)-coupled receptors as mechanosensors mediating myogenic vasoconstriction

Despite the central physiological function of the myogenic response, the underlying signalling pathways and the identity of mechanosensors in vascular smooth muscle (VSM) are still elusive. In contrast to present thinking, we show that membrane stretch does not primarily gate mechanosensitive transi...

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Main Authors: y Schnitzler, Michael Mederos, Storch, Ursula, Meibers, Simone, Nurwakagari, Pascal, Breit, Andreas, Essin, Kirill, Gollasch, Maik, Gudermann, Thomas
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2008
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2599876/
https://ncbi.nlm.nih.gov/pubmed/18987636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.233
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