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A G protein–coupled, IP3/protein kinase C pathway controlling the synthesis of phosphaturic hormone FGF23
Dysregulated actions of bone-derived phosphaturic hormone fibroblast growth factor 23 (FGF23) result in several inherited diseases, such as X-linked hypophosphatemia (XLH), and contribute substantially to the mortality in kidney failure. Mechanisms governing FGF23 production are poorly defined. We h...
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| 出版年: | JCI Insight |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Clinical Investigation
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6777913/ https://ncbi.nlm.nih.gov/pubmed/31484825 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.125007 |
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