MON-LB087 Synthesis of Osteocyte-Derived Phosphaturic Hormone FGF23 via IP3/PKC Signaling Downstream of the Extra-Large Gα Subunit (XLαs)

Dysregulated actions of the bone-derived phosphaturic hormone FGF23 result in several inherited diseases and contribute substantially to the morbidity and mortality in renal failure. Molecular mechanisms governing FGF23 production are poorly defined. Parathyroid hormone (PTH) can stimulate FGF23 pro...

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發表在:J Endocr Soc
Main Authors: He, Qing, Shumate, Lauren, Matthias, Julia, Aydin, Cumhur, Wein, Marc, Spatz, Jordan, Plagge, Antonius, Divieti Pajevic, Paola, Bastepe, Murat
格式: Artigo
語言:Inglês
出版: Endocrine Society 2019
主題:
Bone and Mineral Metabolism
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6550714/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-MON-LB087
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