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Catalytic Enantioselective Carbonyl Propargylation Beyond Preformed Carbanions: Reductive Coupling and Hydrogen Auto-Transfer

Chiral metal complexes catalyze enantioselective carbonyl propargylation via reductive coupling or as hydrogen auto-transfer processes, in which reactant alcohols serve dually as reductant and carbonyl proelectrophile. Unlike classical propargylation protocols, which rely on allenylmetal reagents or...

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Publicado en:ChemCatChem
Autores principales: Ambler, Brett R., Woo, Sang Kook, Krische, Michael J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777576/
https://ncbi.nlm.nih.gov/pubmed/31588251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cctc.201801121
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