TDP2 negatively regulates axon regeneration by inducing SUMOylation of an Ets transcription factor

In Caenorhabditis elegans, the JNK MAP kinase (MAPK) pathway is important for axon regeneration. The JNK pathway is activated by a signaling cascade consisting of the growth factor SVH‐1 and its receptor tyrosine kinase SVH‐2. Expression of the svh‐2 gene is induced by axonal injury in a process inv...

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Bibliografiska uppgifter
I publikationen:EMBO Rep
Huvudupphovsmän: Sakai, Yoshiki, Hanafusa, Hiroshi, Pastuhov, Strahil Iv, Shimizu, Tatsuhiro, Li, Chun, Hisamoto, Naoki, Matsumoto, Kunihiro
Materialtyp: Artigo
Språk:Inglês
Publicerad: John Wiley and Sons Inc. 2019
Ämnen:
Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776894/
https://ncbi.nlm.nih.gov/pubmed/31393064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201847517
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