Insulin-producing organoids engineered from islet and amniotic epithelial cells to treat diabetes

Maintaining long-term euglycemia after intraportal islet transplantation is hampered by the considerable islet loss in the peri-transplant period attributed to inflammation, ischemia and poor angiogenesis. Here, we show that viable and functional islet organoids can be successfully generated from di...

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Publicat a:Nat Commun
Autors principals: Lebreton, Fanny, Lavallard, Vanessa, Bellofatto, Kevin, Bonnet, Romain, Wassmer, Charles H., Perez, Lisa, Kalandadze, Vakhtang, Follenzi, Antonia, Boulvain, Michel, Kerr-Conte, Julie, Goodman, David J., Bosco, Domenico, Berney, Thierry, Berishvili, Ekaterine
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776618/
https://ncbi.nlm.nih.gov/pubmed/31582751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12472-3
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