The Effects of Neoadjuvant Chemoradiation in Locally Advanced Rectal Cancer—The Impact in Intratumoral Heterogeneity

Purpose: Intratumoral genetic heterogeneity (ITGH) is a common feature of solid tumors. However, little is known about the effect of neoadjuvant chemoradiation (nCRT) in ITGH of rectal tumors that exhibit poor response to nCRT. Here, we examined the impact of nCRT in the mutational profile and ITGH...

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Detaylı Bibliyografya
Yayımlandı:Front Oncol
Asıl Yazarlar: Bettoni, Fabiana, Masotti, Cibele, Corrêa, Bruna R., Donnard, Elisa, dos Santos, Filipe F., São Julião, Guilherme P., Vailati, Bruna B., Habr-Gama, Angelita, Galante, Pedro A. F., Perez, Rodrigo O., Camargo, Anamaria A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2019
Konular:
Oncology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776613/
https://ncbi.nlm.nih.gov/pubmed/31612112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00974
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