Genetic interaction networks mediate individual statin drug response in Saccharomyces cerevisiae

Eukaryotic genetic interaction networks (GINs) are extensively described in the Saccharomyces cerevisiae S288C model using deletion libraries, yet being limited to this one genetic background, not informative to individual drug response. Here we created deletion libraries in three additional genetic...

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Detalles Bibliográficos
Publicado en:NPJ Syst Biol Appl
Main Authors: Busby, Bede P., Niktab, Eliatan, Roberts, Christina A., Sheridan, Jeffrey P., Coorey, Namal V., Senanayake, Dinindu S., Connor, Lisa M., Munkacsi, Andrew B., Atkinson, Paul H.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776536/
https://ncbi.nlm.nih.gov/pubmed/31602312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41540-019-0112-5
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