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Effect of Domestication on the Spread of the [PIN+] Prion in Saccharomyces cerevisiae

Prions (infectious proteins) cause fatal neurodegenerative diseases in mammals. In the yeast Saccharomyces cerevisiae, many toxic and lethal variants of the [PSI+] and [URE3] prions have been identified in laboratory strains, although some commonly studied variants do not seem to impair cell growth....

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Detalhes bibliográficos
Main Authors: Kelly, Amy C., Busby, Ben, Wickner, Reed B.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4096356/
https://ncbi.nlm.nih.gov/pubmed/24812307
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.165670
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