The impact of the genetic background on gene deletion phenotypes in Saccharomyces cerevisiae

Loss‐of‐function (LoF) mutations associated with disease do not manifest equally in different individuals. The impact of the genetic background on the consequences of LoF mutations remains poorly characterized. Here, we systematically assessed the changes in gene deletion phenotypes for 3,786 gene k...

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Detalhes bibliográficos
Publicado no:Mol Syst Biol
Main Authors: Galardini, Marco, Busby, Bede P, Vieitez, Cristina, Dunham, Alistair S, Typas, Athanasios, Beltrao, Pedro
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901017/
https://ncbi.nlm.nih.gov/pubmed/31885205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20198831
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