The impact of the genetic background on gene deletion phenotypes in Saccharomyces cerevisiae

Loss‐of‐function (LoF) mutations associated with disease do not manifest equally in different individuals. The impact of the genetic background on the consequences of LoF mutations remains poorly characterized. Here, we systematically assessed the changes in gene deletion phenotypes for 3,786 gene k...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Mol Syst Biol
Main Authors: Galardini, Marco, Busby, Bede P, Vieitez, Cristina, Dunham, Alistair S, Typas, Athanasios, Beltrao, Pedro
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2019
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6901017/
https://ncbi.nlm.nih.gov/pubmed/31885205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20198831
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