A mechanism for the activation of the mechanosensitive Piezo1 channel by the small molecule Yoda1

Mechanosensitive Piezo1 and Piezo2 channels transduce various forms of mechanical forces into cellular signals that play vital roles in many important biological processes in vertebrate organisms. Besides mechanical forces, Piezo1 is selectively activated by micromolar concentrations of the small mo...

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Bibliografski detalji
Izdano u:Nat Commun
Glavni autori: Botello-Smith, Wesley M., Jiang, Wenjuan, Zhang, Han, Ozkan, Alper D., Lin, Yi-Chun, Pham, Christine N., Lacroix, Jérôme J., Luo, Yun
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776524/
https://ncbi.nlm.nih.gov/pubmed/31582801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12501-1
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