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CircCDR1as upregulates autophagy under hypoxia to promote tumor cell survival via AKT/ERK(½)/mTOR signaling pathways in oral squamous cell carcinomas

Autophagy, as an important non-selective degradation mechanism, could promote tumor initiation and progression by maintaining cellular homeostasis and the cell metabolism as well as cell viability. CircCDR1as has been shown to function as an oncogene in cancer progression, however, it remains largel...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Death Dis
Main Authors: Gao, Ling, Dou, Zhi-Chao, Ren, Wen-Hao, Li, Shao-Ming, Liang, Xiao, Zhi, Ke-Qian
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776509/
https://ncbi.nlm.nih.gov/pubmed/31582727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1971-9
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