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Polyacetate and Polycarbonate RNA: Acylating Reagents and Properties

Acylation of RNA at 2′-OH groups is widely applied in mapping RNA structure and recently for controlling RNA function. Reactions are described that install the smallest 2-carbon acyl groups on RNA—namely, 2′-O-acetyl and 2′-O-carbonate groups. Hybridization and thermal melting experiments are perfor...

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Bibliografiske detaljer
Udgivet i:Org Lett
Main Authors: Habibian, Maryam, Velema, Willem A., Kietrys, Anna M., Onishi, Yoshiyuki, Kool, Eric T.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6775763/
https://ncbi.nlm.nih.gov/pubmed/31268332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.9b01526
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