TARGETING MUC1-C INHIBITS TWIST1 SIGNALING IN TRIPLE-NEGATIVE BREAST CANCER

The oncogenic MUC1-C protein and the TWIST1 epithelial-mesenchymal transition transcription factor (EMT-TF) are aberrantly expressed in triple-negative breast cancer (TNBC) cells. However, there is no known association between MUC1-C and TWIST1 in TNBC or other cancer cells. Here we show that MUC1-C...

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Veröffentlicht in:Mol Cancer Ther
Hauptverfasser: Hata, Tsuyoshi, Rajabi, Hasan, Yamamoto, Masaaki, Jin, Caining, Ahmad, Rehan, Zhang, Yan, Kui, Ling, Li, Wei, Yasumizu, Yota, Hong, Deli, Miyo, Masaaki, Hiraki, Masayuki, Maeda, Takahiro, Suzuki, Yozo, Takahashi, Hidekazu, Samur, Mehmet, Kufe, Donald
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774902/
https://ncbi.nlm.nih.gov/pubmed/31308076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-19-0156
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