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MUC1-C ACTIVATES BMI1 IN HUMAN CANCER CELLS
BMI1 is a component of the PRC1 complex that is overexpressed in breast and other cancers, and promotes self-renewal of cancer stem-like cells. The oncogenic mucin 1 (MUC1) C-terminal (MUC1-C) subunit is similarly overexpressed in human carcinoma cells and has been linked to their self-renewal. Ther...
Kaydedildi:
| Yayımlandı: | Oncogene |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5436937/ https://ncbi.nlm.nih.gov/pubmed/27893710 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.439 |
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