Partial Leptin Reduction as an Insulin Sensitization and Weight Loss Strategy

The physiological role of leptin is thought to be a driving force to reduce food intake and increase energy expenditure. However, leptin therapies in the clinic have failed to effectively treat obesity, predominantly due to a phenomenon referred to as leptin resistance. The mechanisms linking obesit...

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Publicado en:Cell Metab
Main Authors: Zhao, Shangang, Zhu, Yi, Schultz, Robbie D., Li, Na, He, Zhenyan, Zhang, Zhuzhen, Caron, Alexandre, Zhu, Qingzhang, Sun, Kai, Xiong, Wei, Deng, Hui, Sun, Jia, Deng, Yingfeng, Kim, Min, Lee, Charlotte E., Gordillo, Ruth, Liu, Tiemin, Odle, Angela K., Childs, Gwen V., Zhang, Ningyan, Kusminski, Christine M., Elmquist, Joel K., Williams, Kevin W., An, Zhiqiang, Scherer, Philipp E.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774814/
https://ncbi.nlm.nih.gov/pubmed/31495688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2019.08.005
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