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Promiscuous G-Protein-Coupled Receptor Inhibition of Transient Receptor Potential Melastatin 3 Ion Channels by Gβγ Subunits
Transient receptor potential melastatin 3 (TRPM3) is a nonselective cation channel that is inhibited by Gβγ subunits liberated following activation of Gα(i/o) protein-coupled receptors. Here, we demonstrate that TRPM3 channels are also inhibited by Gβγ released from Gα(s) and Gα(q). Activation of th...
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| 發表在: | J Neurosci |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Society for Neuroscience
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6774412/ https://ncbi.nlm.nih.gov/pubmed/31451581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0882-19.2019 |
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