Promiscuous G-Protein-Coupled Receptor Inhibition of Transient Receptor Potential Melastatin 3 Ion Channels by Gβγ Subunits

Transient receptor potential melastatin 3 (TRPM3) is a nonselective cation channel that is inhibited by Gβγ subunits liberated following activation of Gα(i/o) protein-coupled receptors. Here, we demonstrate that TRPM3 channels are also inhibited by Gβγ released from Gα(s) and Gα(q). Activation of th...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:J Neurosci
Hlavní autoři: Alkhatib, Omar, da Costa, Robson, Gentry, Clive, Quallo, Talisia, Bevan, Stuart, Andersson, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2019
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774412/
https://ncbi.nlm.nih.gov/pubmed/31451581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0882-19.2019
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky