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Clinical genetic testing for APOL1: Are we there yet?

Endstage renal disease (ESRD) disproportionately affects African Americans, who are 2–4 times more likely than European Americans to develop ESRD. Two independent variants of the Apolipoprotein L1 (APOL1) gene, G1 and G2, have been associated with a 7 to 10-fold greater risk of developing non-diabet...

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Dettagli Bibliografici
Pubblicato in:Semin Nephrol
Autori principali: Young, Bessie A., Fullerton, Stephanie Malia, Wilson, James G., Cavanaugh, Kerri, Blacksher, Erika, Spigner, Clarence, Himmelfarb, Jonathan, Burke, Wylie
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774255/
https://ncbi.nlm.nih.gov/pubmed/29110763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semnephrol.2017.07.009
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