Clinical genetic testing for APOL1: Are we there yet?

Endstage renal disease (ESRD) disproportionately affects African Americans, who are 2–4 times more likely than European Americans to develop ESRD. Two independent variants of the Apolipoprotein L1 (APOL1) gene, G1 and G2, have been associated with a 7 to 10-fold greater risk of developing non-diabet...

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Bibliografiske detaljer
Udgivet i:Semin Nephrol
Main Authors: Young, Bessie A., Fullerton, Stephanie Malia, Wilson, James G., Cavanaugh, Kerri, Blacksher, Erika, Spigner, Clarence, Himmelfarb, Jonathan, Burke, Wylie
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774255/
https://ncbi.nlm.nih.gov/pubmed/29110763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semnephrol.2017.07.009
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