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Clinical genetic testing for APOL1: Are we there yet?

Endstage renal disease (ESRD) disproportionately affects African Americans, who are 2–4 times more likely than European Americans to develop ESRD. Two independent variants of the Apolipoprotein L1 (APOL1) gene, G1 and G2, have been associated with a 7 to 10-fold greater risk of developing non-diabet...

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Detalhes bibliográficos
Publicado no:Semin Nephrol
Main Authors: Young, Bessie A., Fullerton, Stephanie Malia, Wilson, James G., Cavanaugh, Kerri, Blacksher, Erika, Spigner, Clarence, Himmelfarb, Jonathan, Burke, Wylie
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774255/
https://ncbi.nlm.nih.gov/pubmed/29110763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semnephrol.2017.07.009
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