Clinical genetic testing for APOL1: Are we there yet?

Endstage renal disease (ESRD) disproportionately affects African Americans, who are 2–4 times more likely than European Americans to develop ESRD. Two independent variants of the Apolipoprotein L1 (APOL1) gene, G1 and G2, have been associated with a 7 to 10-fold greater risk of developing non-diabet...

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Bibliografske podrobnosti
izdano v:Semin Nephrol
Main Authors: Young, Bessie A., Fullerton, Stephanie Malia, Wilson, James G., Cavanaugh, Kerri, Blacksher, Erika, Spigner, Clarence, Himmelfarb, Jonathan, Burke, Wylie
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774255/
https://ncbi.nlm.nih.gov/pubmed/29110763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semnephrol.2017.07.009
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