Clinical genetic testing for APOL1: Are we there yet?

Endstage renal disease (ESRD) disproportionately affects African Americans, who are 2–4 times more likely than European Americans to develop ESRD. Two independent variants of the Apolipoprotein L1 (APOL1) gene, G1 and G2, have been associated with a 7 to 10-fold greater risk of developing non-diabet...

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Gepubliceerd in:Semin Nephrol
Hoofdauteurs: Young, Bessie A., Fullerton, Stephanie Malia, Wilson, James G., Cavanaugh, Kerri, Blacksher, Erika, Spigner, Clarence, Himmelfarb, Jonathan, Burke, Wylie
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774255/
https://ncbi.nlm.nih.gov/pubmed/29110763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semnephrol.2017.07.009
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