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Distinct Roles of Synaptic and Extrasynaptic NMDA Receptors in Excitotoxicity

Excitatory synaptic activity governs excitotoxicity and modulates the distribution of NMDA receptors (NMDARs) among synaptic and extrasynaptic sites of central neurons. We investigated whether NMDAR localization was functionally linked to excitotoxicity by perturbing F-actin, a cytoskeletal protein...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Sattler, Rita, Xiong, Zhigang, Lu, Wei-Yang, MacDonald, John F., Tymianski, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6774093/
https://ncbi.nlm.nih.gov/pubmed/10627577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-01-00022.2000
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