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An Integrated System Biology Approach Yields Drug Repositioning Candidates for the Treatment of Heart Failure

Identifying effective pharmacological treatments for heart failure (HF) patients remains critically important. Given that the development of drugs de novo is expensive and time consuming, drug repositioning has become an increasingly important branch. In the present study, we propose a two-step drug...

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Veröffentlicht in:Front Genet
Hauptverfasser: Yang, Guodong, Ma, Aiqun, Qin, Zhaohui S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773955/
https://ncbi.nlm.nih.gov/pubmed/31608126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00916
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