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A computational systems biology approach for identifying candidate drugs for repositioning for cardiovascular disease
We report an in silico method to screen for receptors or pathways that could be targeted to elicit beneficial transcriptional changes in a cellular model of a disease of interest. In our method we integrate: (i) a dataset of transcriptome responses of a cell line to a panel of drugs; (ii) two sets o...
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| Publicado no: | Interdiscip Sci |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5403631/ https://ncbi.nlm.nih.gov/pubmed/27778232 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12539-016-0194-3 |
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