Applications of Genome-Wide Screening and Systems Biology Approaches in Drug Repositioning

Modern drug discovery through de novo drug discovery entails high financial costs, low success rates, and lengthy trial periods. Drug repositioning presents a suitable approach for overcoming these issues by re-evaluating biological targets and modes of action of approved drugs. Coupling high-throug...

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Main Authors: Elyas Mohammadi, Rui Benfeitas, Hasan Turkez, Jan Boren, Jens Nielsen, Mathias Uhlen, Adil Mardinoglu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2020-09-01
Colecção:Cancers
Assuntos:
drug repositioning
genomic screens
machine learning
systems pharmacology
systems medicine
Acesso em linha:https://www.mdpi.com/2072-6694/12/9/2694
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