Positive Effects of PI3K/Akt Signaling Inhibition on PTEN and P53 in Prevention of Acute Lymphoblastic Leukemia Tumor Cells

Purpose: The PI3K/Akt signaling pathway regulates cell growth, proliferation and viability in hematopoietic cells. This pathway always dysregulates in acute lymphoblastic leukemia (ALL). PTEN and P53 are tumor suppressor genes correlated with PI3K/Akt signaling pathway, and both have a tight link in...

Full description

Saved in:
Bibliographic Details
Published in:Adv Pharm Bull
Main Authors: Naderali, Elahe, Valipour, Behnaz, Khaki, Amir Afshin, Soleymani Rad, Jafar, Alihemmati, Alireza, Rahmati, Mohammad, Nozad Charoudeh, Hojjatollah
Format: Artigo
Language:Inglês
Published: Tabriz University of Medical Sciences 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773944/
https://ncbi.nlm.nih.gov/pubmed/31592121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/apb.2019.056
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items