Positive Effects of PI3K/Akt Signaling Inhibition on PTEN and P53 in Prevention of Acute Lymphoblastic Leukemia Tumor Cells

Purpose: The PI3K/Akt signaling pathway regulates cell growth, proliferation and viability in hematopoietic cells. This pathway always dysregulates in acute lymphoblastic leukemia (ALL). PTEN and P53 are tumor suppressor genes correlated with PI3K/Akt signaling pathway, and both have a tight link in...

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Publicat a:Adv Pharm Bull
Autors principals: Naderali, Elahe, Valipour, Behnaz, Khaki, Amir Afshin, Soleymani Rad, Jafar, Alihemmati, Alireza, Rahmati, Mohammad, Nozad Charoudeh, Hojjatollah
Format: Artigo
Idioma:Inglês
Publicat: Tabriz University of Medical Sciences 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773944/
https://ncbi.nlm.nih.gov/pubmed/31592121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15171/apb.2019.056
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