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Antileukemic activity of novel adenosine derivatives

The present study investigated the effect of cladribine (CLA) and six of its derivatives containing a formamidine group at position 6 (CLA-FDM, CLA-FPAZ, CLA-FPIR, CLA-FPIP, CLA-FHEX, and CLA-FMOR) on acute promyelocytic, lymphoblastic, and acute monocytic leukemia cells. The role of ATR kinase in d...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Poczta, Anastazja, Rogalska, Aneta, Łukawska, Małgorzata, Marczak, Agnieszka
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773697/
https://ncbi.nlm.nih.gov/pubmed/31575977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-50509-1
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