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Novel iodoacetamido benzoheterocyclic derivatives with potent antileukemic activity are inhibitors of STAT5 phosphorylation

Signal Transducer and Activator of Transcription 5 (STAT5) protein, a component of the STAT family of signaling proteins, is considered to be an attractive therapeutic target because of its involvement in the progression of acute myeloid leukemia. In an effort to discover potent molecules able to in...

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Detalhes bibliográficos
Publicado no:Eur J Med Chem
Main Authors: Romagnoli, Romeo, Baraldi, Pier Giovanni, Prencipe, Filippo, Lopez-Cara, Carlota, Rondanin, Riccardo, Simoni, Daniele, Hamel, Ernest, Grimaudo, Stefania, Pipitone, Rosaria Maria, Meli, Maria, Tolomeo, Manlio
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724257/
https://ncbi.nlm.nih.gov/pubmed/26629859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2015.11.022
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