HNF4A is essential for the active epigenetic state at enhancers in mouse liver

Cell fate determination is influenced by interactions between master transcription factors (TFs) and cis-regulatory elements. Hepatocyte nuclear factor 4 alpha (HNF4A), a liver-enriched TF, acts as a master controller in specification of hepatic progenitor cells by regulating a network of TFs to con...

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Udgivet i:Hepatology
Main Authors: Thakur, Avinash, Wong, Jasper C. H., Wang, Evan Y., Lotto, Jeremy, Kim, Donghwan, Cheng, Jung-Chien, Mingay, Matthew, Cullum, Rebecca, Moudgil, Vaishali, Ahmed, Nafeel, Tsai, Shu-Huei, Wei, Wei, Walsh, Colum P., Stephan, Tabea, Bilenky, Misha, Fuglerud, Bettina M., Karimi, Mohammad M., Gonzalez, Frank J., Hirst, Martin, Hoodless, Pamela A.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773525/
https://ncbi.nlm.nih.gov/pubmed/30933372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.30631
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