Widespread recovery of methylation at gametic imprints in hypomethylated mouse stem cells following rescue with DNMT3A2

BACKGROUND: Imprinted loci are paradigms of epigenetic regulation and are associated with a number of genetic disorders in human. A key characteristic of imprints is the presence of a gametic differentially methylated region (gDMR). Previous studies have indicated that DNA methylation lost from gDMR...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Epigenetics Chromatin
Main Authors: Thakur, Avinash, Mackin, Sarah-Jayne, Irwin, Rachelle E., O’Neill, Karla M., Pollin, Gareth, Walsh, Colum
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118886/
https://ncbi.nlm.nih.gov/pubmed/27895716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-016-0104-2
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados