High-endothelial cell-derived S1P regulates dendritic cell localization and vascular integrity in the lymph node

While the sphingosine-1-phosphate (S1P)/sphingosine-1-phosphate receptor-1 (S1PR1) axis is critically important for lymphocyte egress from lymphoid organs, S1PR1-activation also occurs in vascular endothelial cells (ECs), including those of the high-endothelial venules (HEVs) that mediate lymphocyte...

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Vydáno v:eLife
Hlavní autoři: Simmons, Szandor, Sasaki, Naoko, Umemoto, Eiji, Uchida, Yutaka, Fukuhara, Shigetomo, Kitazawa, Yusuke, Okudaira, Michiyo, Inoue, Asuka, Tohya, Kazuo, Aoi, Keita, Aoki, Junken, Mochizuki, Naoki, Matsuno, Kenjiro, Takeda, Kiyoshi, Miyasaka, Masayuki, Ishii, Masaru
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2019
Témata:
Immunology and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773441/
https://ncbi.nlm.nih.gov/pubmed/31570118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41239
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