Lysophosphatidic acid receptors LPA(4) and LPA(6) differentially promote lymphocyte transmigration across high endothelial venules in lymph nodes

Naive lymphocytes continuously migrate from the blood into lymph nodes (LNs) via high endothelial venules (HEVs). To extravasate from the HEVs, lymphocytes undergo multiple adhesion steps, including tethering, rolling, firm adhesion and transmigration. We previously showed that autotaxin (ATX), an e...

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Detalhes bibliográficos
Publicado no:Int Immunol
Main Authors: Hata, Erina, Sasaki, Naoko, Takeda, Akira, Tohya, Kazuo, Umemoto, Eiji, Akahoshi, Noriyuki, Ishii, Satoshi, Bando, Kana, Abe, Takaya, Kano, Kuniyuki, Aoki, Junken, Hayasaka, Haruko, Miyasaka, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885216/
https://ncbi.nlm.nih.gov/pubmed/26714589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxv072
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