Lysophosphatidic acid receptors LPA(4) and LPA(6) differentially promote lymphocyte transmigration across high endothelial venules in lymph nodes

Naive lymphocytes continuously migrate from the blood into lymph nodes (LNs) via high endothelial venules (HEVs). To extravasate from the HEVs, lymphocytes undergo multiple adhesion steps, including tethering, rolling, firm adhesion and transmigration. We previously showed that autotaxin (ATX), an e...

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Dettagli Bibliografici
Pubblicato in:Int Immunol
Autori principali: Hata, Erina, Sasaki, Naoko, Takeda, Akira, Tohya, Kazuo, Umemoto, Eiji, Akahoshi, Noriyuki, Ishii, Satoshi, Bando, Kana, Abe, Takaya, Kano, Kuniyuki, Aoki, Junken, Hayasaka, Haruko, Miyasaka, Masayuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2016
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4885216/
https://ncbi.nlm.nih.gov/pubmed/26714589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxv072
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