Fibroblastic reticular cell-derived lysophosphatidic acid regulates confined intranodal T-cell motility

Lymph nodes (LNs) are highly confined environments with a cell-dense three-dimensional meshwork, in which lymphocyte migration is regulated by intracellular contractile proteins. However, the molecular cues directing intranodal cell migration remain poorly characterized. Here we demonstrate that lys...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Takeda, Akira, Kobayashi, Daichi, Aoi, Keita, Sasaki, Naoko, Sugiura, Yuki, Igarashi, Hidemitsu, Tohya, Kazuo, Inoue, Asuka, Hata, Erina, Akahoshi, Noriyuki, Hayasaka, Haruko, Kikuta, Junichi, Scandella, Elke, Ludewig, Burkhard, Ishii, Satoshi, Aoki, Junken, Suematsu, Makoto, Ishii, Masaru, Takeda, Kiyoshi, Jalkanen, Sirpa, Miyasaka, Masayuki, Umemoto, Eiji
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2016
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4755752/
https://ncbi.nlm.nih.gov/pubmed/26830463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10561
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