Involvement of the Lysophosphatidic Acid-Generating Enzyme Autotaxin in Lymphocyte-Endothelial Cell Interactions

Autotaxin (ATX) is a secreted protein with lysophospholipase D activity that generates lysophosphatidic acid (LPA) from lysophosphatidylcholine. Here we report that functional ATX is selectively expressed in high endothelial venules (HEVs) of both lymph nodes and Peyer’s patches. ATX expression was...

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Detalhes bibliográficos
Main Authors: Nakasaki, Tae, Tanaka, Toshiyuki, Okudaira, Shinichi, Hirosawa, Michi, Umemoto, Eiji, Otani, Kazuhiro, Jin, Soojung, Bai, Zhongbin, Hayasaka, Haruko, Fukui, Yoshinori, Aozasa, Katsuyuki, Fujita, Naoya, Tsuruo, Takashi, Ozono, Keiichi, Aoki, Junken, Miyasaka, Masayuki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2008
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2570145/
https://ncbi.nlm.nih.gov/pubmed/18818380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.071153
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