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A Concise, Modular Antibody-Oligonucleotide Conjugation Strategy Based on Disuccinimidyl Ester Activation Chemistry

Synthesis of antibody-oligonucleotide conjugates has enabled the development of highly sensitive bioassays for specific epitopes in the laboratory and clinic. Most synthetic schemes to generate these hybrid molecules require expensive reagents, significant quantities of input antibody, and multi-ste...

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Bibliografiske detaljer
Udgivet i:Chembiochem
Main Authors: Li, Gang, Moellering, Raymond E.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773266/
https://ncbi.nlm.nih.gov/pubmed/30767357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201900027
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