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Long-Term Nicotine Adaptation in Caenorhabditis elegans Involves PKC-Dependent Changes in Nicotinic Receptor Abundance

Chronic exposure to nicotine leads to long-term changes in both the abundance and activity of nicotinic acetylcholine receptors, processes thought to contribute to nicotine addiction. We have found that in Caenorhabditis elegans, prolonged nicotine treatment results in a long-lasting decrease in the...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Waggoner, Laura E., Dickinson, Kari A., Poole, Daniel S., Tabuse, Yo, Miwa, Johji, Schafer, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6773091/
https://ncbi.nlm.nih.gov/pubmed/11102488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-23-08802.2000
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